Motor-learning based activities may improve functional ability in adults with severe cerebral palsy: A controlled pilot study

BACKGROUND: Cerebral palsy (CP) is a neurodevelopmental disturbance characterized by impaired control of movement. Function often decreases and 15% adults are classified as severely affected (Gross Motor Classification Scale III-V). Little known about interventions that aim to improve functional abilities in this population. OBJECTIVE: To evaluate 12-week intervention based on motor learning principles ability with severe CP. METHODS: 16 (36±10 years, GMFCS III-V) were enrolled divided into an group (Active group) standard care (Control group). Primary outcome measure was Gross Measure (GMFM-88). Secondary measures neurological status. The Active measured at baseline, after the one-month follow-up. Control baseline one month. RESULTS: Analysis showed statistically significant improvement GMFM-88 for from post assessment compared (group difference: 5 points, SE 14.5, p = 0.008, CI: 1.2 8.7). Improvements maintained Results screening no clear tendencies. CONCLUSIONS: study provides support activities may gross function